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Barbara Bardoni Selected Research

RNA-Binding Proteins (RNA-Binding Protein)

1/2018Modeling Fragile X Syndrome in Drosophila.
1/2018HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.
1/2018New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons.
1/2017The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?
9/2015The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.
10/2014Fragile X Syndrome: from molecular pathology to therapy.
1/2012Intellectual disabilities, neuronal posttranscriptional RNA metabolism, and RNA-binding proteins: three actors for a complex scenario.
12/2011A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.
5/2011Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.
8/2010The role of G-quadruplex in RNA metabolism: involvement of FMRP and FMR2P.
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Barbara Bardoni Research Topics

Disease

24Fragile X Syndrome (Martin Bell Syndrome)
01/2022 - 06/2002
21Intellectual Disability (Idiocy)
01/2021 - 09/2003
3Autism Spectrum Disorder
01/2022 - 01/2021
3Down Syndrome (Down's Syndrome)
01/2021 - 01/2012
3Schizophrenia (Dementia Praecox)
01/2021 - 01/2017
3Autistic Disorder (Autism)
01/2018 - 01/2014
2Neurodevelopmental Disorders
01/2021 - 01/2019
2Rett Syndrome (Rett's Disorder)
01/2021 - 01/2012
2Fragile X Tremor Ataxia Syndrome
12/2019 - 05/2013
1Epilepsy (Aura)
01/2017
1Seizures (Absence Seizure)
01/2015
1Facioscapulohumeral Muscular Dystrophy
03/2013
1Neoplasms (Cancer)
07/2009
1Cicatrix (Scar)
10/2004
1Multiple Sclerosis
04/2004

Drug/Important Bio-Agent (IBA)

18RNA-Binding Proteins (RNA-Binding Protein)IBA
01/2018 - 06/2002
14Fragile X Mental Retardation ProteinIBA
01/2018 - 09/2003
7RNA (Ribonucleic Acid)IBA
01/2018 - 01/2007
7Proteins (Proteins, Gene)FDA Link
01/2017 - 04/2004
2Type 2 Cyclic Nucleotide PhosphodiesterasesIBA
01/2022 - 01/2019
2Messenger RNA (mRNA)IBA
12/2019 - 05/2013
23' Untranslated Regions (3' UTR)IBA
01/2015 - 05/2013
1Guanosine Monophosphate (5' Guanylic Acid)IBA
01/2022
1Adenosine Monophosphate (AMP)IBA
01/2022
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2021
1CalciumIBA
01/2021
1Inositol (Myoinositol)IBA
01/2021
1diethylstilbestrol monophosphate (PDES)IBA
01/2021
1Cholecystokinin Receptors (Cholecystokinin Receptor)IBA
01/2021
1Cadherins (E-Cadherin)IBA
01/2021
1Small Interfering RNA (siRNA)IBA
12/2019
15' Untranslated Regions (5' UTR)IBA
12/2019
1Peptides (Polypeptides)IBA
12/2019
1NucleotidesIBA
01/2019
1Eukaryotic Initiation Factor-4EIBA
01/2017
1Peptide Initiation Factors (Initiation Factor)IBA
01/2017
1Carisoprodol (Soma)FDA LinkGeneric
01/2015
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2015
1Protein Isoforms (Isoforms)IBA
03/2013
1ElementsIBA
07/2009
1Drosophila ProteinsIBA
10/2004
1DNA (Deoxyribonucleic Acid)IBA
04/2004

Therapy/Procedure

5Therapeutics
01/2021 - 10/2014
1Cognitive Training
01/2018